Human characters must drain a Critter for the Innocent Shard, then drain Hogger for the Wanted Shard. Bring both to the Soul Broker in Goldshire.

Undead characters must drain a Critter for the Innocent Shard, then drain Maggot Eye for the Wanted Shard. Bring both to the Soul Broker in the Undercity.

Alliance characters must find the Dead Acolyte in the Jasperlode Mine, then get the Powerless Artifact from a Warlock Trainer. Head back to the Acolyte to get the Blood Offering. Head straight to Gakin the Darkbinder in the Mage Quarter of Stormwind to cleanse the debuff.

Horde characters must find the Dead Acolyte in Tirisfal Glades close to the Scarlet Monastery, then bring it to a Warlock Trailer to get the Powerless Artifact. Go back to the Acolyte, use the Artifact, then head to Carendin Halgar in the Magic Quarter of the Undercity to get rid of the debuff.

Human characters must kill Dark Strand Fanatics, found in southern Darkshore

Undead characters must find the Sadistic Fiend, an elite enemy, in a cave found in east Silverpine Forest. Cast Curse of Recklessness on the Sadistic Fiend and kill the elite.

All characters must hunt down Zixil, a wandering vendor in the Hillsbrad Foothills. Players must purchase a unique Bomb from Zixil (costing five gold). Head to Durnholde Keep in Hillsbrad, and find an interactive Rubble NPC in the northeastern part of the ruins. Use the Demolition Explosives item on the Rubble to uncover a Chest.

Purchased from Waylaid Supply vendors after reaching Honored with the new faction, the Azeroth Commerce Authority/Durotar Supply and Logistics.

All characters must obtain three items from three different mobs in their respective starting zones. Players must get the Ominous Tome from the first enemy listed, Blood or Legs from the second, and Jawbones or Skulls from the third.

After acquired, head to the summoning circles in either Stormwind or the Undercity to summon an elite demon, which must be defeated.

Purchased from Grizzby in the Ratchet Inn after completing a series of quests requiring several items – 24 Fish Oil, 20 Dark Iron Ordinance, and 16 Shredder Turbochargers. Players have at least 5 Gold to interact with Grizzby.

All characters must defeat a new elite enemy in Redridge Mountains named Incinerator Gar'im. Incinerator Gar'im spawns in the south east of the zone in a cave.

The Haunt Rune is earned after completing the Level 2 quest that introduces the Rune System. These quests can be started in each starting zone, and asks players to find a different item nearby.

Undead characters must find a chest in the Spider cave

Human characters must defeat the Frozen Murloc at Stonecairne Lake with Fire damage (Immolate & Imp Firebolts)

Undead characters must defeat the Frozen Murloc north of the Tirisfal Lake with Fire damage (Immolate & Imp Firebolts)

Alliance characters must either defeat Delmanis the Hated in Darkshore. Alternatively, Alliance players can shoot a Shadow-damage dealing spell at the Demonic Remains in the Loch Modan archeological ruins. This spawns an elite that, when killed, drops the Rune.

Horde characters must drain Supervisor Lugwizzle in the Venture Co area of the northern Barrens to get a Soul of Greed. Head south to find a Hungry Idol, and offer the Soul to it. Alternatively, Horde players can kill enemies in Beren's Peril in Silverpine Forest to get a Tortured Soul. Cast Life Tap, then interact with the Tortured Soul to spawn an elite enemy, which drops the Rune.

All characters must follow a branching questline with multiple requirements and locations involved. To begin with, players must go to the southern Barrens to find an NPC named Doan Karhan.

Click on the Altar to begin a ritual which will spawn waves of Demons. Once the Ritual is complete, speak to the Mysterious Traveler who appears, then head back to Doan Karhan. The final step of the quest asks players to speak to one more NPC just a few steps away.

To get the Grimoire of Synergy Rune, you will need to first complete the lengthy Metamorphosis questline from Phase One. After this, at Level 30, you will be called back to the Warlock Camp in the Barrens. Speak with Raszel Ander to begin the quest A Solid Foundation and receive an Invisibility Potion.

Once you get a Soul Vessel, go to Mannoroc Cavern in south Desolace and look for an Altar. Turn in the quest, and a Level 40 Elite named Des'Altek will spawn. Defeat this elite to get the Rune of Synergy as well as a Neverending Soul Vessel, a 5-minute cooldown item that negates the Soul Shard cost of the next spell cast.

To get the Rune of Burning Darkness, which unlocks the Shadow and Flame Rune, head to Desolace and look for an extinguished Campfire just northwest of the Kodo Graveyard (slightly north of the "D" in "Kodo" on the map). Pick up the quest Highway Robbery, then go directly northwest to find Kormek's Hut on the ridge overlooking the graveyard. Turn in Highway Robbery, pick up the next quest On The Lam, then head to Booty Bay.

Go to the border of the Wetlands and the Arathi Highlands and look for a boat underneath the Thandol Span bridge. Jump down into the water and interact with this boat to teleport to the far eastern shore of the Highlands. Talk to Illari Duskfeather, choose either Dialogue option, and kill her to get Illari's Key. Open the nearby Illari's Loot Cache to get the Rune.

To get the Rune of Invocation, go to Stromgarde Keep in the Arathi Highlands and kill Syndicate Conjurors until you get 10 Conjuror's Pendant items. Get a Soul of the Void by using Drain Soul on a Voidwalker nearby, then combine the Pendants and the Soul to summon a Void Seeker. These items can only be combined on the Void Prism, a special location on the top floor of a house in Stromgarde. Kill the Void Seeker to get the Rune of Invocation.

To get the Rune of Wickedness, which unlocks the Dance of the Wicked Rune, you must find the Reckless Warlock somewhere in Azeroth. This new NPC can spawn outside the Gurubashi Arena, in Thousand Needles, in the Satyr area of Desolace, or in the very back of the Ogre cave in the Alterac Mountains. Speak with him to get the Brimstone Carving. Then, use Hellfire to damage yourself over and over again until the Brimstone Carving turns into the Rune of Wickedness.

To get the Shadowflame Rune, head to about (80, 82.5) in Desolace to find Shadowbreak Ravine. Travel to the back of this area to find a Sacrificial Altar. Cast Shadow Ward on yourself, then interact with the Altar to start channeling. You will take nearly lethal damage if you aren't able to mitigate via Shadow Ward, as you cannot heal normally during this channel. Survive the channel by using this, consumables and other buffs, and special Shadow Resist gear. Completing the channeling process summons a Level 38 elite enemy named Seductress Ceeyna. Kill this enemy to get the Rune.

The Rune of Forbidden Knowledge (and the Demonic Knowledge Rune) unlocks via the Phase Two Dark Rider questline. To begin, head to Ariden's Camp in Deadwind Pass at around (52, 34.5) in the zone. Talk to the Dalaran Agent at the camp to get Ariden's Sigil. He will ask you to recover seven Dalaran Relics from Dark Riders throughout Azeroth. Each of the Dark Riders is about as difficult as a Dungeon boss at 40, but because all classes have one Rune tied to the SoD Dark Rider, it's not too hard to get a five to ten-man group together.

The Dark Riders can be found in Duskwood, Deadwind Pass, Swamp of Sorrows, Badlands, The Barrens, Desolace, and the Arathi Highlands. After killing each one, head back to the Dalaran Agent and give him the recovered Dalaran Relics. After completing each quest (which reward about 1.5g at Level 40), the Agent will give you a bag containing the Rune.