Purchase Freshwater Snapper Bait from a faction-neutral vendor in Hillsbrad Foothills. Climb onto a boat in the lake near Tarren Mill and use the bait on the water to spawn a unique elite enemy.

Purchased from Grizzby in the Ratchet Inn after completing a series of quests requiring several items – 24 Fish Oil, 20 Dark Iron Ordinance, and 16 Shredder Turbochargers. Players have at least 5 Gold to interact with Grizzby.

Dwarf characters must find a Rustling Bush in Dun Morogh, and cast Hunter's Mark on it to spawn a unique enemy.

Orc and Troll characters must must find a Rustling Bush in the Durotar, and cast Hunter's Mark on it to spawn a unique enemy.

All characters must go to a cave in the Wetlands to defeat a unique elite Owl named Carrodin.

All characters must kill Furbolgs across Ashenvale to get the Gnarled Wand of Wild Magic. Combine this with a Greater Magic Wand, then defeat the final boss of the Wailing Caverns to get a Hypnotic Crystal. Finally, head to a unique vendor in the Stonetalon Mountains to trade the items for the Rune.

Purchased from Waylaid Supply vendors after reaching Honored with the new faction, the Azeroth Commerce Authority/Durotar Supply and Logistics.

Dwarf characters must gather Dun Morogh Pig Meat to spawn a unique elite named Jorul, who can be tamed or killed to earn the Rune.

Orc and Troll characters must gather Durotar Pig Meat to spawn a unique elite named Raluk, who can be tamed or killed to earn the Rune.

Horde players must use a Fishing Harpoon to spear an elite Shark enemy near Ratchet. The Fishing Harpoon can be purchased nearby on the docks.

Alliance players must kill the Defias Scout, just above Sentinel Hill. The elite despawns very quickly, so be prepared to stun and nuke him. Alternatively, players can use the Gnarled Harpoon to kill an elite enemy in the waters near a Beached Sea Turtle.

Dwarf characters must acquire Rabbit Musk from Rockjaw Troggs, then tame a Rabbit and bring it to Amberstill Ranch.

Orc and Troll characters must acquire Adder Pheromone from the Quillboars, then tame an Adder and bring it to Razor Hill.

Dwarf characters must kill Vagash, an elite quest enemy in Dun Morogh

Orc and Troll characters must kill Sarkoth, an elite quest enemy in Durotar

All characters earn Chimera Shot after completing the Level 2 quest that introduces the Rune system, each of which requires players to kill one of several basic enemies in the starting zone.

Alliance players must kill Furbolg in Darkshore to get Crab Treats, then feed them to a Young Reef Crawler.

Horde players must summon the unique Grizzled Protector elite by killing Ferocious Grizzled Bears in Silverpine Forest.

Head to the Arathi Highlands and locate an elite Level 35 enemy named Needletooth at about (66, 60) in the Witherbark Village lake. Kill Needletooth to get the Rune of Steady Shot.

To get the Rune of Expose Weakness, head to the Badlands and kill Dustbelcher Ogres, in the south and west of the zone, until one drops a Primitive Drawing. Accept the quest that the item triggers, then go to Hemet Nesingwary in northern Stranglethorn Vale.

Kill it to get the Crimson Trophy Quill, and go back to Hemet Nesingwary to turn it in and get the Rune.

The Rune of Close Combat (and the Melee Specialist rune) unlocks via the Phase Two Dark Rider questline. To begin, head to Ariden's Camp in Deadwind Pass at around (52, 34.5) in the zone. Talk to the Dalaran Agent at the camp to get Ariden's Sigil. He will ask you to recover seven Dalaran Relics from Dark Riders throughout Azeroth. Each of the Dark Riders is about as difficult as a Dungeon boss at 40, but because all classes have one Rune tied to the SoD Dark Rider, it's not too hard to get a five to ten-man group together.

The Dark Riders can be found in Duskwood, Deadwind Pass, Swamp of Sorrows, Badlands, The Barrens, Desolace, and the Arathi Highlands. After killing each one, head back to the Dalaran Agent and give him the recovered Dalaran Relics. After completing each quest (which reward about 1.5g at Level 40), the Agent will give you a bag containing the Rune.

To get the Rune of Invigoration, both factions must first head to the Swamp of Sorrows. On the road that forks south from the western entrance from Deadwind Pass, Hunters will find a new NPC named Amaryllis Webb. Buy her Entomology Starter Kit for 50 silver, which contains a Guide and a Net, then head to three zones to capture three different creatures.

In the Arathi Highlands , go to Northfold Manor at (31, 28) and look for the Hay Weevil in any of the Stables in the nearby area. Use the net on the Weevil to catch it. It should look like a small purple spider.

In Stranglethorn Vale , head to Lake Nazferiti and look for a stump at (45, 19). Use the Net on the Arbor Tarantula on the stump. It should look like a small orange spider.

To get the Rune of the Trapper (and thus the Trap Launcher Rune), head to Desolace, and look for an extinguished Campfire just northwest of the Kodo Graveyard (slightly north of the "D" in "Kodo" on the map). Pick up the quest Highway Robbery, then go directly northwest to find Kormek's Hut on the ridge overlooking the graveyard. Turn in Highway Robbery, pick up the next quest On The Lam, then head to Booty Bay.

Go to the border of the Wetlands and the Arathi Highlands and look for a boat underneath the Thandol Span bridge. Jump down into the water and interact with this boat to teleport to the far eastern shore of the Highlands. Talk to Illari Duskfeather, choose either Dialogue option, and kill her to get Illari's Key. Open the nearby Illari's Loot Cache to get the Rune.

To get the Rune of the Scapper (which unlocks the Dual Wield Specialization Rune), go to an area just southwest of Hemet Nesingwary's camp in northern Stranglethorn Vale, around the first troll ruins as you head southwest from the famous hunter. You'll know you're in the right spot when you get a "Danger!" buff. Make sure you have the Flare ability trained, and use it to reveal a Bloodscalp Guerrilla while in the area (if you are close to its current location). Kill it to get the Rune.