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After synthesizing a cure at the Emily May Foundation, Marvel's Spider-Man 2 players will need to administer it to Doctor Connors to help counteract the effects of Kraven's serum. This means heading over to the doc's house in Astoria, where they'll then need to solve a puzzle involving a piano in order to figure out what became of the Lizard after he returned home.

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When players first arrive at the house, they'll need to head downstairs and examine the photograph in the kitchen. It turns out that this is actually a secret switch and pulling it will reveal a touch panel and the game's very own piano puzzle. To solve it, players will have to key in a four-digit code, though figuring out what this code is might be a little tricky for some players.

What's the Piano Puzzle Code in Marvel's Spider-Man 2

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For those in a hurry, the Marvel's Spider-Man 2 piano puzzle code is 4441. This means that players will need to press the pink key on the right three times and then the green one on the left once. Doing so will result in a doorway opening to the left of the panel, allowing players to head down into Dr. Connors' secret lab. Once there, they'll need to check the surveillance footage and then head into the panic room in order to progress.

How to Find the Piano Puzzle Code in Marvel's Spider-Man 2

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For those who prefer to figure things out for themselves, there are a few big clues that can guide players toward the Marvel's Spider-Man 2 piano puzzle solution. The most notable of these is the barn in the top right-hand corner of the code screen, which just so happens to match the one on the child's piano in the living room. Also, if players check out the mobile in Connors' son's room, it will play a bit of Old MacDonald and Pete will remark that he is clearly an animal lover.

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Armed with this information, players should head into the living room and interact with the child's piano toy. They'll have a choice of pressing three buttons here but should go with the barn in the center. This will result in the piano playing the first bar of Old MacDonald, revealing that the keys needed for the first four notes are pink, pink, pink, and green. Players can then play these notes on the touch panel in the kitchen to gain access to the secret lab.

How to Skip the Piano Puzzle in Marvel's Spider-Man 2

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If players would rather just skip the piano puzzle entirely they can do so by pausing the game while interacting with the touch panel. Upon doing so, they should have the option to Skip Activity, which will allow them to enter the lab without having to key in the four notes. This is a little similar to the process for skipping cutscenes in Marvel's Spider-Man 2, as both options are accessed via the pause menu.

Marvel's Spider-Man 2 is available now exclusively for the PS5.