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The entire journey of Leon in Capcom's Resident Evil 4 remake is all about saving Ashley Graham from the clutches of Los Illuminados. At the head of this religious movement is Osmund Saddler, a bio-weapons research chief turned fanatic, who has been sending the infected to stop Leon from completing his objective.
While this big bad has plenty of manpower at his disposal, Leon will eventually catch up to Saddler, culminating in one last boss fight to take down the leader once and for all. This guide will provide all the vital information needed on how to defeat Osmund Saddler in Resident Evil 4 and get Ashley to safety to complete the mission.
How to Defeat Osmund Saddler in Resident Evil 4 Remake
With Saddler now revealing his true form as a slimy arachnid-like monster, it would be understandable for players to feel slightly apprehensive. After all, this is supposed to be the most dangerous individual in the whole game. Thankfully, things are not as worrisome as they appear to be.
Saddler Boss Fight First Phase
By looking closely at Saddler, his weak points are very apparent. There are six eyes that can be shot at by players to inflict heavy damage on the boss, but the real problem is having limited space to work with. Always keep a distance from Saddler, shoot at the weak points, and if he gets stunned, get up close to have Leon stab him in the main eyeball. A good handgun like the Red9 will do well here, as will a shotgun like the Striker if the distance is short enough. For those that cannot get the timing down right when the eyes are open, use an SMG like the LE 5.
In addition, during the fight, moving around will get Saddler close to some explosive barrels conveniently placed in the arena. Use them for an advantage to stagger this monster, and get close to deal heavy damage with a nice stab. Be sure to also use Grenades and Mines to keep the pressure up.
There will also be other smaller enemies that will join the fight, but focusing on Saddler alone should be the main focus. If enough damage is dealt before he can summon his allies, it will be easier for Leon to finish the entire encounter with fewer problems. Eventually, Saddler will seemingly fall, but like all good boss fights, here comes the second phase.
Saddler Boss Fight Second Phase
Leon will now find himself face-to-face with a huge hulking mess of slimy tendrils and innards, with Saddler's once punchable face now reduced to a giant glowing orb. Now is the time to bring out all the big guns like the Killer7 Magnum, the Stingray Rifle, or the good old shotguns to do as much damage to the orb as possible.
The boss will try to hit Leon, so look out for the Evade prompt to avoid any damage. If the tentacles are raised up high, simply run to the opposite end to avoid the slam attack. Keep it up, and Ada will come to the rescue once more by throwing a special rocket launcher to Leon, grab the weapon and fire it into the orb to end the reign of Saddler.
Saddler Boss Fight Hack
While the boss fight against Saddler is not the toughest there is in the game, there is a way to make it even easier from the start. Before entering the arena, either purchase a rocket launcher from the Merchant, or grab one from storage. Once the fight starts, simply fire the rocket launcher at Saddler's main eye to end the first phase immediately.
For players who happen to have the Infinite Rocket Launcher, this boss fight will become a procession, and Leon will live to see another day much more smoothly than before.
Resident Evil 4 (2023) is available on PC, PS4, PS5, and Xbox Series X/S.
