BioShock has a bunch of different powerful weapons and upgrades scattered throughout its semi-open world that players can use to obliterate their enemies, one of them being Plasmids. Plasmids grant players powerful abilities that they can use in combat either offensively or defensively. Jack can inject himself with different Plasmids, but only two Plasmids can be equipped at a time, so, players have to choose two of the best-suited Plasmids before their battles. However, players can’t switch or change Plasmids on the go, or during combat, so they have to look for special vending machines to change things up.

Plasmids are not only useful for combat, but players can also use them to unlock doors, accessing certain areas, or finding a Little Sister. Those who’ve already seen and used Plasmids in BioShock know how useful these abilities can be, but it’s important to switch Plasmids to get through some tough sections of the game.

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How to Switch Plasmids in BioShock

In order to switch Jack’s equipped Plasmids, players will need to find a particular vending machine called Gene-Bank. These look similar to other vending machines that can be found throughout the game, however, Gene-Banks have an image of a muscular man holding a DNA strand over his head. Here’s an image of a Gene-Bank found in BioShock:

bioshock gene bank

There are several Gene-Banks scattered throughout Rapture, and almost any time players come across a group of vending machines, they'll find a Gene-Bank there. To switch a Plasmid, all players have to do is interact with the Gene-Bank, select the Plasmid they want to equip, and choose a button on either one of Jack’s hands to assign it the Plasmid. This will successfully change the previous Plasmid with the new one that players select. It’s important to note that players can only equip two Plasmids at a time, so it’s better to keep switching them for different encounters.

As the game progresses, players will be able to upgrade the Plasmids and get the ability to equip more than two Plasmids at a time. These upgrades will cost ADAM, which is a currency players can earn by harvesting or saving Little Sisters in BioShock. Players can now go ahead and use these Plasmids to their advantage in older BioShock games since a new BioShock game is not coming any time soon.

BioShock is available now for PC, PS4, Xbox One, Xbox 360, and PS3.

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