Even before the introduction of its anime by the studio Gekkou, My One-Hit Kill Sister was especially known for its interesting twist on the overpowered main character, a staple isekai trope. The story follows Asahi Ikusaba, a high school student who gets transported to another world where he remains weak and devoid of any ‘cheat abilities.'
Unfortunately for him, his older sister, Mayu, also gets transported to that world and gains all the skills that Asahi would have liked. And she’s not just stronger than he is but also has a brother complex that upsets Asahi. But they have to work together in this world, using Asahi’s knowledge of game worlds and Mayu’s strength to complete various quests. Their unlikely situation creates many comedic moments in the story. Here are ten other anime that share similarities with My One-Hit Kill Sister.
10 Isekai Cheat Magician
Like My One-Hit Kill Sister, Isekai Cheat Magician, features the protagonist, Taichi Nishimura, who is transported to a fantasy world along with female company. In this case, he moves with his friend, Rin Azuma, with whom he has an interesting relationship with a romantic undertone.
After they move to this fantasy world known as Altianutz, both Taichi, and Rin discover their great power while becoming adventurers. But there is more to discover, like the reason why Taichi was brought to this world and the great role he must play in saving it.
9 Do You Love Your Mom and Her Two-Hit Multi-Target Attacks?
This anime is basically My One-Hit Kill Sister but with the sister replaced by a mother. Created by J.C.Staff and written by Iida Pochi, the anime follows Masato Oosuki as he navigates his complicated relationship with his mother, Mamako Oosuki.
Inside the fantasy world they get transported to, Masato tries to display some skill but is constantly overshadowed by his mother, who is stronger and better at fighting. They form a team with three girls in the game and carry out quests that lead to an interesting discovery about their game world.
8 Kemono Michi: Rise Up
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Kemono Michi: Rise Up is another Isekai anime with an interesting twist. The protagonist, Genzo Shibata, is a professional wrestler with a deep love for animals. He is suddenly transported during a wrestling match, and faced with a request from the princess of that new world, Princess Altena.
She wishes him to save her kingdom from daemon beasts, but Genzo denies her request in a way only a wrestler like Genzo would. He then works toward the goal of convincing people to take the daemon beasts as pets instead of killing them.
7 Combatants Will Be Dispatched!
Sentouin Roku-gou, the character at the heart of Combatants Will Be Dispatched!, is given the serious task of infiltrating a planet much like Earth, but which is actually a fantasy world at war with a group called the Demon King’s Army. He goes there with Kisaragi Alice, his assistant android.
Overly confident in his skills, Roku-gou ends up having to face the Demon King’s Army and fulfill the wishes of the kingdom’s princess. But he’s not just fighting against the Demon King’s Army; he continues his original mission of spying and remaining an agent of the Kisaragi Corporation.
6 Cautious Hero: The Hero Is Overpowered but Overly Cautious
In Cautious Hero, Seiya Ryuuguuin is the perfect isekai protagonist on paper: he’s strong, with a host of skills and moves on his side, and also quick at learning the ropes of anything. His major flaw, however, is that he lacks the recklessness and impulsivity that characterize other heroes.
Instead, he faces every situation with a great deal of caution, and this upsets Ristarte, the inexperienced goddess who summons him to save Gaeabrande. Cautious Hero creates an interesting balance of high stakes and funny moments and interactions.
5 Tsukimichi: Moonlit Fantasy
Tsukimichi: Moonlit Fantasy and My One-Hit Kill Sister have some significant differences but are similar in the sense that both stories follow the adventures of a male protagonist who is weak and struggles to find his place in the new world.
In Tsukimichi: Moonlit Fantasy, Makoto Misumi gets left behind and changed by his goddess in a new world. She takes away his ability to understand humans but gives him the ability to understand all other beings. With this ability, Makoto creates a community of non-human beings but still feels the desire to be with other humans.
4 The Devil is a Part-Timer!
Based on the similarly titled light novel by Satoshi Wagahara, The Devil is a Part-Timer! follows Satan and his general, Alciel, as they escape Ente Isla and settle in modern-day Tokyo. Satan takes on the name Sadao Maou and begins work at a fast-food restaurant. But for a character like Sadao Maou, things can’t always remain so simple.
This anime and My One-Hit Kill Sister both contain elements of action and comedy and the struggle to adapt to a changed reality. However, the story in The Devil is a Part-Timer! can be considered more complicated.
3 Log Horizon
Mamare Touno’s Log Horizon is set in a fictional MMORPG game world called Elder Tale that keeps players trapped after the game is updated. The main character, Shiroe, who belonged to the ‘Debauchery Tea Party’ guild, is the great strategist behind his friends’ attempt to survive the game world.
Shiroe and his friends, Naotsugu and Akatsuki, battle monsters, create allies, and work to create a world similar to the one that was taken from them. Both Log Horizon and My One-Hit Kill Sister handle the complex nature of power and relationships.
2 The Rising Of The Shield Hero
Like My One-Hit Kill Sister, The Rising of the Shield Hero includes elements of combat and adventure as the characters battle monsters and other foes in their quest to save their worlds. However, The Rising of the Shield Hero tells its story in a darker tone.
Naofumi Iwatani is transported to the kingdom of Melromarc, where he faces the consequences and loneliness of a false accusation. Despite the challenges and obstacles standing in his way, Naofumi gradually grows as a hero and gains the respect of the people.
1 KonoSuba: God's Blessing on This Wonderful World!
KonoSuba: God's Blessing on This Wonderful World! and My One-Hit Kill Sister both have a comedic approach to Isekai, deconstructing the staple tropes and clichés with humor and satire. In both shows, a group of unlikely characters form teams to take on the challenges of the new world they find themselves in.
KonoSuba, written by Natsume Akatsuki, follows Kazuma Sato, a reclusive NEET who dies and is transported to a fantasy world. He is joined by a group of quirky individuals, including a useless goddess, a wizard obsessed with explosion magic, and a masochistic crusader.