SPOILERS AHEAD

The relationship between Baldur's Gate 3 and Dungeons and Dragons is symbiotic, meaning BG3 learned a lot in adapting the DnD 5e ruleset and DnD could learn from plenty of the changes made to its formula in the game. More importantly, many Baldur's Gate 3 fans are constantly starting new Tavs, Origin Characters, and Durges just to experience it all over again. The anticipation for Baldur's Gate 3 DLC is understandably high as a result, but it's uncertain when and if that'll happen. Instead, however, it's possible to translate Larian's take on Faerun to the table and "continue" the story of BG3 as a custom, homebrewed campaign.

It's easy enough to translate the custom characters and companions of Baldur's Gate 3 into DnD characters; it's pretty much outlined for every character, with a few modifications of course. That said, there are also plenty of "unfinished" stories that could serve well as BG3 DLC or as completely homebrewed campaigns, with this world and characters translated from pixels to pen and paper.

Fallout in the City

DMs could easily find ways to tie together many elements that are ongoing in the city as of Baldur's Gate 3's ending, any of them really. Practically every duke is killed, including Gortash and potentially Ravengard based on player choices, and this could create a fun power vacuum as the power of the city tries to rebuild. This opens up a lot of potential plots as people try to seize or restore power, as well as a lot of political RP. Meanwhile, the Underduke intends to restrengthen the Thieves Guild after the dealings with the Zhentarim (which a DM could take in any direction), and of course, it stands to reason many Cult of Bhaal worshippers are still alive somewhere in the city. These could serve as little one-offs or short campaigns, while it's possible to see ways DMs could bring them together. Perhaps a low-ranking member from the Cult of Bhaal seizes the chance to restore the cult after Orin's death and manipulates the crumbling power hierarchy.

The Fallout of Karsus

On its own or in conjunction with the above, it could be interesting to see if a new character becomes the Chosen of Gale, God of Ambition, to influence PCs or be a PC to deal with this and the fallout of the Crown's reforging. At the same time, Mystra having Netherese power could be tied in the above storylines, if not outright standalone as well.

The War Between Selune and Shar

Selune or Shar can get the upper hand in their war depending on player choices in Baldur's Gate 3, with a Sharran Shadowheart rebuilding her cloister with new Dark Justiciars or a Selunite Shadowheart being on the run from Sharran Assassins. Again, either of these hooks could serve as standalone campaigns or be tied into some new emerging plot unifying other ongoings in the city.

Mephistopheles' Revenge

Dark Urge in Baldur's Gate 3

Perhaps one of the best storylines for possible Baldur's Gate 3 DLC or as a homebrew campaign deals with the archdevil Mephistopheles. He has plenty of reasons to hold a grudge against the possible player characters, particularly if someone were to convert a Dark Uge BG3 character. If someone chooses not to ascend Astarion, then that is 7,000 souls Mephistopheles has been denied. Players also learn that The Dark Urge and Gortash are responsible for the heist of the Crown of Karsus. Mephistopheles seeking revenge not only seems like a great possible BG3 DLC, but it's open to interpretation, letting DMs have a lot of fun in this pocket. Any DM could create a great campaign of nearly any length dealing with Mephistopheles attempting to get back at the characters.

Spawn in the Underdark

It's worth mentioning that the Vampire Spawn would ideally be living peacefully or terrorizing the Underdark; their fate is left ambiguous. Not only does this give DMs a lot to work with in a Mephistopheles-based Baldur's Gate 3 campaign, but it could also serve as a standalone element in an Underdark adventure.

Avernus Adventures

If players want to set something in Avernus, then it would be simple enough to work in Karlach (potentially alongside Wyll and/or Tav) as well. One ending sees her return to the hated plane, and this could involve new methods to escape, brand new stories, and several other options. This could make a great side quest in any infernal dealings or it could be a major plot point in the aforementioned Mephistopheles campaign.

The Githyanki Civil War

baldurs-gate-3-orpheus

If players don't want to be restricted to the city of Baldur's Gate or to Avernus, then the Astral Plane has a lot to offer. It could be something like Mind Flayer society dealing with the aftermath of the Netherbrain, it could be the ongoings with the Githyanki, and either would make great as full-fledged campaigns or miniature adventures. After the events of the game, Orpheus, Lae'Zel, Tav, or any combination of those could be leading war against Vlaakith. There are also Githzerai rebels that are later involved per Lae'Zel's epilogue in Baldur's Gate 3.

Really, a DnD campaign based on Baldur's Gate 3 can take any loose story thread, headcanon, or inspiration, and it would translate very well. It'll be interesting to see how the relationship between the two continues to grow in the future.